Combined detection of postoperative CA50 CA199 CA242 CEA observation of pancreatic cancer.docVIP

 PAGE \* MERGEFORMAT 10 Combined detection of postoperative CA50 CA199 CA242 CEA observation of pancreatic cancer [Abstract] Objective To observe the serum of patients with pancreatic cancer carbohydrate antigen 50 (CA50), carbohydrate antigen 199 (CA199), carbohydrate antigen 242 (CA242), carcinoembryonic antigen CEA recurrence of pancreatic cancer the clinical value of diagnosis . Methods chemiluminescence and enzyme-linked immunosorbent assay, were detected in 41 cases of pancreatic cancer patients after serum CA50, CA199, CA242, CEA levels, and continuous monitoring. Results 34 cases of pancreatic cancer recurrence CA50, CA199, CA242, CEA was elevated in 25 cases (73.5%), 28 patients (82.4%), 27 cases (79.4%), CEA25 cases (73.5%), 4 single tumor marker levels were higher than those without recurrence group , and the differences were statistically significant (P lt;0.01). Conclusion Postoperative joint determination of CA199, CA50, CEA, CA242 could prompt early postoperative recurrence of pancreatic cancer, increase the sensitivity of diagnosis of pancreatic cancer recurrence. [Keywords:] CA199 CA50 CEA CA242 tumor marker of pancreatic cancer High rate of clinical recurrence of pancreatic cancer, so early diagnosis of recurrence of pancreatic cancer is very important, and the use of a single item sensitivity and specificity of detection is not ideal. We used serum tumor-related substances carbohydrate antigen 199 (carbohydrate antigen199 , CA199) and carbohydrate antigen, carbohydrate antigen 50 (carbohydrate antigen50, CA50), CEA (carcinoembryonic antigen CEA), carbohydrate antigen 242 (carbohydrate antigen 242, CA242) combination of methods to detect serum levels after to investigate the clinical recurrence of pancreatic cancer diagnosis. 1 Materials and methods 1.1 Materials 41 cases I, Ⅱ, after curative resection of pancreatic cancer patients are forward-looking dynamic observation of the object, according to Japan Pancreas Socie