Compound Yimu oral pain model of mice.docVIP

 PAGE \* MERGEFORMAT 12 Compound Yimu oral pain model of mice Study: Cattle Stellerite, Liu Huili, Miao out three, Lijiang Hua [Abstract] Objective To investigate oral compound Yimu the treatment of dysmenorrhea. Methods used diethylstilbestrol fed oxytocin-made solutions and dysmenorrhea model of pain induced by hot plate and acetic acid writhing method in mice and other experimental observations Compound Yimu oral analgesia. RESULTS Compound Yimu can significantly improve oral mouse hot plate pain threshold of pain caused by that increase the pain threshold was significantly increased, compound Yimu oral group had a significant extension of acetic acid in mice latency of the writhing reaction was significantly reduced within 10 min writhing number of occurrences, the compound can significantly extend Yimu oral diethylstilbestrol plus oxytocin induced writhing model in mice dysmenorrhea incubation period, the mice were significantly reduced torsional 10min Body times. CONCLUSION Compound Yimu good oral analgesic effect. [Keywords:] compound Yimu oral solution, dysmenorrhea, model Mainly by the oral compound Yimu Motherwort, Angelica, Chuanxiong, composed of wood and other drugs, with blood circulation of qi, blood pain of power, the clinical efficacy of dysmenorrhea due to blood stasis is better. To verify its role and to explore its features, observed on 3 of the oral pain model and the impact of dysmenorrhea model. 1 Materials and equipment 1.1 Drugs and reagents oral compound Yimu by beings Pharmaceutical Co., Ltd. Henan bamboo production, batch number 050701, Yimu oral, commercial Qiulv Yuan Pharmaceutical Co, lot number 050108, diethylstilbestrol tablets, Shanghai, Hong Xinyi Jie Pharmaceutical Co, lot number 050301, oxytocin injection, Shanghai First Biochemical Pharmaceutical Co, lot number 050717, acetic acid, Tianjin Chemical Reagent Co Kay, batch number 050410. 1.2 Animals Kunming mice of clean grade, weighing 18 ~ 21 g, were pur