Consecutive isolates of Escherichia coli resistant phenotype and SXT resistance-associated gene A population study of oxazole.docVIP

 PAGE \* MERGEFORMAT 9 Consecutive isolates of Escherichia coli resistant phenotype and SXT resistance-associated gene A population study of oxazole Author: Wang Wei, Zu-huang Mi Mao Jianfeng Xu Weizhen [Abstract] Objective To investigate the clinical isolates of Escherichia coli drug resistance and mouth oxazole compound sulfamethoxazole (SMZ / TMP) resistance genes related to the situation. Methods of clinical measurement of continuous separation of the 60 E. coli to 19 antimicrobial agents of the sensitivity of polymerase chain reaction (PCR) detection of SMZ / TMP resistance-related genes (sul1, dfrA1, dfrA17). Results 60 of sul1, dfrA1, dfrA17 gene positive were 34 (56.7%), 1 (1.7%), 35 (58.3%). Conclusion multi-drug resistance in clinical isolates of Escherichia coli serious; A mouth oxazole sulfamethoxazole resistance-related genes carrying a high rate. [Keywords:] Escherichia coli; compound sulfamethoxazole mouth oxazole; resistance gene ABSTRACT Objective To investigate the drug resistance and drug resistance  related trimethoprim  sulfamethoxazole genes in Excherichia coli. Method Microdilution tests were performed to detect susceptibility of 60 strains of Escherichia coli to 19 antimicrobial agents and drug resistance  related trimethoprim  sulfamethoxazole were detected by PCR . Result The positive rates of sul1, dfrA1 and dfrA17 genes in 60 clinical strains of Escherichia coli were 56.7%, 1.7%, 58.3%, respectively. Conclusions There are multiple  drug resistance and high positive rate of drug resistance  related trimethoprim  sulfamethoxazde genes in Escherichia coli isolated from the hospital. KEY WORDS Escherichia coli; Trimethoprim  sulfamethoxazole; Resistant genes Over the years, Escherichia coli (Escherichia coli, EC) has been the major pathogens of hospital infection. EC bacteria to β  lactam and aminoglycoside antibiotics commonly used, including multi-drug resistance occurs, the relevant resistance genes have been