Different times after intracerebral hemorrhage in the brain edema formation mechanism.docVIP
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Different times after intracerebral hemorrhage in the brain edema formation mechanism
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Different times after intracerebral hemorrhage in the brain edema formation mechanism
[Keywords:] cerebral hemorrhage, cerebral edema
Primary intracerebral hemorrhage (ICH of disability and mortality were higher in patients with cerebral edema after intracerebral hemorrhage is an important cause of increased symptoms, seriously affecting the patient’s prognosis. In recent years a growing number of scholars have conducted in-depth study and made some new progress. now different times after intracerebral hemorrhage in the brain edema formation machine to produce a description.
1 edema after intracerebral hemorrhage in the formation mechanism of ultra-early
1.1 hematoma mass effect and secondary hemorrhage
Mass effect is mainly caused by cerebral edema and mechanical stress caused by increased intracranial pressure. Wagner et al [1] completed in 3h after porcine hemorrhage model of tissue plasminogen activator (tissue plasminogen activator, tPA) injection blood clot, 1h after the melting of the clot suction, tPA dissolves blood clots and suction in the treatment can eliminate 72% of the original hematoma volume, can significantly relieve the pressure on the surrounding brain tissue, reduced volume of cerebral edema, and prevent further vasogenic edema. Qureshi et al [2] that the continued expansion of hematoma after intracerebral hemorrhage within the first 3h the main reason for the deterioration of nerve function. The traditional view that hematoma enlargement is due to a single bleeding artery or vein continued bleeding or rebleeding But Mayer [3] that it is more than parts of brain tissue around the hematoma bleeding again.
1.2 hematoma and blood clots within the retraction of plasma protein exudation
Wagner et al [4] observed that porcine brain lobe hemorrhage 1h, water higher than the contralateral brain around the hematoma 10%, hematoma in the area around the plasma protein immune activity, and this time intravasc
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