Effect of telmisartan on left ventricular remodeling in patients with hypertension and plasma B-type natriuretic peptide.docVIP

 PAGE \* MERGEFORMAT 12 Effect of telmisartan on left ventricular remodeling in patients with hypertension and plasma B-type natriuretic peptide [Abstract] Objective To investigate the effect of telmisartan on left ventricular remodeling and plasma BNP concentration. Methods 94 patients of hypertension, which is not associated with left ventricular hypertrophy (LVH 44 patients, 50 patients with LVH, and healthy control group 46 cases. hypertension were treated with telmisartan 80mg qd treatment of 32 weeks. All objects were measured before and after treatment left ventricular mass index (LVMI), BNP, ejection fraction (EF, statistical analysis with SPSS13.0. Results of hypertension LVH LVH group and there was no before and after treatment were significantly different indexes (P lt;0.05), the control group no significant difference (Pgt; 0.05), BNP and LVMI and changes in value of the change in value is related to EF. Conclusion without hypertension , hypertension and left ventricular remodeling is not accompanied by BNP, EF has a significant difference in plasma BNP level may reflect the left ventricular remodeling and left ventricular function. telmisartan to curb and reverse left ventricular remodeling and improve cardiac function with significant effect. [Keywords:] telmisartan, blood pressure, ventricular remodeling, heart failure Abstract Objective To study the effect of telmisarten on left ventricular remodeling and plasma b-type natriuretic peptide (BNP). Methods 94 cases with hypertension formed the experiment group, including 44 cases without left ventricular hypertrophy (LVH) and 50 cases with LVH; 46 normal formed the control group; telmisarten, 80mg, once a day, was administrated to cases in the experiment group and the course lasted for 32 weeks.; LVMI, BNP and ejection fracture (EF) of all the cases in both groups were detected before and after treatment and the results were statistically analyzed by the software SPSS13.0. Results There ex