Emergency high-dose intravenous amiodarone for refractory ventricular tachycardia and - or efficacy of ventricular fibrillation.docVIP

 PAGE \* MERGEFORMAT 12 Emergency high-dose intravenous amiodarone for refractory ventricular tachycardia and / or efficacy of ventricular fibrillation OF: Prince Liu Jing Li Yan Hung Wen-Xiang Zhang Chao [Abstract] Objective: To evaluate the emergency high-dose intravenous amiodarone for refractory ventricular tachycardia and / or ventricular fibrillation and clinical efficacy of the medication experience. Methods: 56 patients with first-aid center after acute myocardial infarction ventricular refractory heart Excessive speed and / or ventricular fibrillation patients, 36 males and 20 females, aged 37 to 73 years, average 46.2 years old. in the attack or arrhythmia after electrical defibrillation loading dose of intravenous amiodarone 150 mg, followed by the first 6 h to 1.0 ~ 1.5 mg / min infusion of amiodarone, 6 h after the 0.5 ~ 1.0 mg / min maintenance; if not satisfied with arrhythmia control interval of 30 min and then injected with 75 ~ 150 mg; both oral amiodarone tablets , each 200 mg, 3 times a day, gradually reduced to maintain a daily oral dose of 1. Results: Intravenous drug use (2.56 + -0.59) d, the amount of the first 24 h IV (1 351 + -192) mg, arrhythmia control rate of 69.6% (39/56); the second 24 h intravenous dosage (759 + -38) mg, the cumulative control rate of arrhythmia was 82.1% (46/56); third intravenous dosage of 24 h (726 + -21 ) mg, the cumulative control rate of arrhythmia 91.1% (51/56). medication occurred during the 7 patients with arrhythmias, drug returned to normal after reduction; 72 h in 6 patients because of disease progression of clinical death. Conclusion: Emergency high-dose intravenous amiodarone after acute myocardial infarction with refractory ventricular tachycardia and fibrillation Heart room safe and effective action. [Keywords:] amiodarone; drug dose; clinical efficacy Abstract Objective: To investigate the clinical efficacy of large dose of amiodarone in treating refractory ventricular tachycardia (VT