Evaluation of heavy metal excretion behavior parameters by exposure to toxic metabolic state in C. elegans.docVIP

 PAGE \* MERGEFORMAT 20 Evaluation of heavy metal excretion behavior parameters by exposure to toxic metabolic state in C. elegans Of: Wuqiu Li, Yang Yi Chao, Da-yong [Abstract] Objective: To study the excretion of heavy metal exposure on the behavior of C. elegans. Methods: For analysis of CdCl2, CrCl2, HgCl2 and Pb (NO3) 2 concentration, respectively 50,100,150 and 200 mol L-1. The average length of discharge cycle parameters used to evaluate the heavy metal exposure to the metabolic state changes in Caenorhabditis elegans. linear regression for the analysis of the average cycle length of excretion of heavy metals concentrations and exposure, exposure to animals, the average length of discharge cycle and pharyngeal pumping rate of the association between exercise . Results: All of the concentration of mercury and lead exposure and the concentration of 100 mol L-1 200 mol L-1 cadmium and chromium exposure can be a significant increase in C. elegans, the average excretion of cycle length. nematode average discharge cycle length with the accompanying heavy metal exposure concentrations are changed features, and the average excretion of cycle length was significantly related to the exposure concentration of heavy metals. in the heavy exposure of the C. elegans pharyngeal pumping movement rate is also significantly related to the average discharge cycle length. In addition, mercury and lead exposure for behavior of nematode excretion of chromium and cadmium exposure than serious. Conclusion: The average excretion of cycle length parameters can effectively evaluate the metabolic state of C. elegans exposed to heavy metals poisoning, and heavy metal exposure in nematode excretion can be observed in the average cycle length and pharyngeal pumping movement rate of significant correlation between. [Keywords:] heavy metal; excretion behavior; metabolic state; C. elegans Caenorhabditis elegans, a free living soil nonparasitic nematode, survives in terrest