Gomi Lingqi Capsule analysis of anti-HIV activity_0.docVIP

 PAGE \* MERGEFORMAT 15 Gomi Lingqi Capsule analysis of anti-HIV activity Of: Zhang rights, Zhang Longqing, Zhang hand Gorge, Jianger Chen, F. Jin, Zhang Lili, Chen Hongshan, Huang Yao Island [Abstract] Objective To detect the flavors of Lingqi Capsules of different HIV (HIV-1) strain replication inhibitory activity, and anti-HIV-1 drug synergies as well as CD4 +, CD8 + lymphocytes in the immune-enhancing activity. Method from the traditional Chinese medicine Extraction of effective parts of flavors Lingqi into capsules, the use of human peripheral blood lymphocytes (PBMC) and human T lymphocyte cell lines (H9 and MT2) training. punch Lingqi capsule results in human PBMC in clinical isolates of HIV- 1018a therapeutic index is 96, in human T lymphocyte cell lines H9 and MT-2 cells of HIV-1 laboratory strain HTLV-Ⅲ B’s therapeutic index of 94 and 181, respectively, determined with Western Zipf more than it HIV-1018c and H9 strains of the virus chronic infection inhibition is weak, it is with the HIV-1 reverse transcriptase inhibitors, protease inhibitors and fusion proteins to prevent viral entry inhibitors have a good synergistic antiviral activity of PBMC increased significantly non-specific antigen phytohemagglutinin (PHA) and Candida antigen specific (candidi) response capability. Conclusions and medicine and more determined than Zipf, Gomi Lingqi ability to inhibit viral capsule weaker, but it is a good synergistic anti- activity and significantly enhanced virus-specific immune activity makes it unique and valuable anti-HIV-1 drugs. [Keywords: HIV, Gomi Lingqi capsule, Zipf multiplicity, inhibitory activity, immunological activity Keywords:: HIV-1, Wuweilingqi capsule, AZT, inhibited activity, immune activity Over the last decade, the global pharmaceutical scientists in the anti-HIV (HIV-1) activity conducted in-depth study, but are also found in traditional Chinese medicine (such as Xiao Chai Hu Tang), single herb (such as shikonin, berberi