Heart failure-related receptors and cytokines in experimental and clinical research of Chinese medicine.docVIP

 PAGE \* MERGEFORMAT 9 Heart failure-related receptors and cytokines in experimental and clinical research of Chinese medicine Abstract [Objective] To investigate the medicine on the heart failure-related receptors and the role of cytokines. [Methods] Chinese medicine treatment of heart failure-related receptor, cytokines, apoptosis, changes in retrospective analysis and research. [Results] The medicine can reduce the Ang Ⅱ, lowered its receptor protein; with the increase of myocardial β-adrenergic receptor density and resistance to chronic heart failure the role of the intervention of the role of cytokines, the treatment of chronic heart failure; can improve myocardial blood supply and enhance cardiac function and inhibit apoptosis in heart failure. [Conclusion] Chinese medicine can inhibit myocardial remodeling, anti-oxidative stress, regulation of neuroendocrine, regulatory cytokines, regulation of apoptosis genes inhibit apoptosis of myocardial cells, improve blood rheology and hemodynamics, regulate immune function and other mechanisms of The treatment of heart failure. Keywords: Heart failure; receptor; cell factor; Review Abstract: [Objective] To explore TCM function on concerned receptors and cell factors of heart failure. [Method] TCM can reduce Ang II, down  regulate receptor albumen, up  regulate cardiac muscle receptor β density and resist chronic heart failure, has intervention of cell factors; it can treat chronic heart failure, improve cardiac muscle blood supply, increase heart function and resist apoptosis of heart failure. [Conclusion] TCM can treat heart failure by inhibiting cardiac muscle re  structure, anti oxidation stress, regulating nerve incretion , adjusting cell factors and apoptosis genes to resist cardiac muscle apoptosis, improving blood rheology and dynamics, regulating immune. Keywords:: heart failure; receptor; cell factors; review Heart failure is a variety of heart diseases leading to