High flux hemofiltration in elderly patients with sepsis triggered myeloid cells in peripheral blood1 receptor expression and function of.docVIP

 PAGE \* MERGEFORMAT 11 High flux hemofiltration in elderly patients with sepsis triggered myeloid cells in peripheral blood1 receptor expression and function of [Keywords:] sepsis; high flux hemofiltration; triggering receptor on myeloid cells 1; tumor necrosis factor-@; interleukin-6 Sepsis was induced by the microorganism invades the human body and the excessive systemic inflammatory response, the elderly (gt; = 60 years) because of its organ aging, dysfunction, and patients with multiple chronic diseases, in some incentives easily excited by septic shock , and multiple organ dysfunction syndrome, mortality up to 50% (1). In recent years, high-throughput hemofiltration (HVHF) sepsis in the elderly, septic shock, multiple organ dysfunction syndrome treatment to obtain significant effect, but its mechanism is still considerable controversy. HVHF previous studies focused on the removal of various pathogenic factors (2), but studies have confirmed the effects of HVHF treatment of sepsis and inflammatory factors in the efficiency of removal without any connection between. myeloid cells triggers receptor 1 (TREM 1) is Bounchon, etc. (3) discovered in 2000, a new immunoglobulin superfamily, is the older infectious diseases of inflammation in the excitation and cascades The key medium, can enhance the impact of inflammation on the body. Therefore, I HVHF observed in elderly peripheral blood mononuclear cells in patients with sepsis the expression of TREM 1, and the treatment of elderly patients with sepsis after peripheral blood mononuclear LPS reactive cells were observed. 1 Materials and Methods 1.1 General information from March 2007 to August 2009 Shaoxing Municipal People’s Hospital, treated in ICU Division .10 elderly patients with sepsis in 20 patients with early fluid resuscitation, antibiotics, intensive glycemic control, and other organs to support the basis of comprehensive treatment , and supplemented by HVHF treatment, 8 males and 2 females,