Hongyexintong soft capsule on hemodynamics of anesthetized dogs.docVIP

 PAGE \* MERGEFORMAT 8 Hongyexintong soft capsule on hemodynamics of anesthetized dogs Of: Licui Bing, Huang Yong, Wang Yonglin, TRADITIONAL [Abstract] Objective To observe Hongyexintong soft capsule on hemodynamics in anesthetized dogs. Method chest anesthetized dogs coronary artery separation to different doses Hongyexintong soft capsules and compound Danshen tablets as control, blood pressure observed after administration the heart rate in anesthetized dogs, cardiac output and coronary blood flow and other hemodynamic parameters. Results Hongyexintong soft capsule on blood pressure in anesthetized dogs Systolic blood pressure (SAP), diastolic blood pressure (DAP), mean arterial pressure (MAP) has antihypertensive effect, significantly increased anesthetized dogs coronary blood flow (CBF, heart rate (HR, compared with the control group, significant difference (P lt;0.05. Conclusion Hongyexintong soft capsules can improve cardiac function, there are certain research and development prospects. [Keywords:] Hongyexintong soft capsules, hemodynamics, anesthetized dogs Abstract: ObjectiveTo investigate hemodynamic changes in anaesthetized dogs after the intravenous injection of Hongyexintong soft capsule.Methods The hemodynamic indexes of open chest dogs were observed after intravenous injection of Hongyexintong soft capsule at different doses, which were compared with Fufangdanshen tablets. ResultsHongyexintong soft capsule had the potency of decreasing the SAP, DAP, MAP, HR and increasing obviously the CBF of the experimental dogs, and the test results in experimental group were significantly different from those in control group (P lt;0.05). ConclusionHongyexintong soft capsule has effect of improving cardiac function, which indicates Hongyexintong soft capsule has a perspective of research and development. Keywords:: Hongyexintong soft capsule; Hemodynamic; Anethetized dogs Hongyexintong soft capsules drug in Ethnic Chinese medicine develope