HPLC determination DAXXK capsules diosgenin content.docVIP

 PAGE \* MERGEFORMAT 8 HPLC determination DAXXK capsules diosgenin content [Abstract] Objective: To establish an accurate DAXXK quantitative quality control methods. Methods: The high-performance liquid chromatography DAXXK main ingredient diosgenin content. Results: DAXXK in diosgenin sample volume within the range of 0.165 ~ 3.389μ g peak area showed good linear relationship between the average recovery was 98. 2%, RSD = 1.7%. Conclusion: The method is simple, convenient and good reproducibility DAXXK used to control the content, reliability high. [Keywords:] DAXXK Determination of diosgenin Determinating the content of diosgenin in Diao xinxuekang capsules by HPLC [Abstract] Objective: To establish the accurate and controlled method in Diao xinxuekang by HPLC.Method: Determinating the content of diosgenin in Diao xinxuekang capsules by HPLC.Results: The linear range of diosgenin in Diao xinxuekang was 0.16 ~ 3.389μ g, the average reconvery was 98.2%, RSD = 1.7%. Conclusion: A simple and accurate method to diosgenin in Diao xinxuekang capsules was established. [Key word] Diao xinxuekang capsules; diosgenin; content determination DAXXK capsule with blood circulation of qi and pain relief, expansion of coronary blood vessels, improving myocardial ischemia and so on. For the prevention and treatment of coronary heart disease, angina, and bleeding resistance of the Chest, dizziness, shortness of breath, palpitations, chest tightness or pain [1]; clinical application of a wide range, because capsules DAXXK the main ingredients of diosgenin [2], existing Pharmacopoeia method for the determination accuracy and reproducibility is not high, we switch to high-performance liquid chromatography, results were satisfactory. An apparatus and reagents Shimadzu LC10ATvp high-performance liquid chromatograph. Dioscin reference substance (China Pharmaceutical and Biological Products Institution, Lot :1539-200001), pure grade pure methanol and the remaining reagents we