IL-12P70 and IFN-- Discretion in predicting acute renal allograft rejection in the application.docVIP

 PAGE \* MERGEFORMAT 17 IL-12P70 and IFN-? Discretion in predicting acute renal allograft rejection in the application Of: Hongliang Qing Huang Zhengyu Ouyang Bin Yang Peisheng Miubin Hua Xue-feng [Abstract] [Objective] To investigate the serum IL-12P70, IL-4, IFN-? Discretion in predicting early renal transplant recipients immune status of the role. [Method] The Third Affiliated Hospital of Sun Yat-sen line of allogeneic kidney transplantation dead Division 52 cases of renal transplant patients, including 28 males and 24 females, mean age 42.3 years, patients were divided into normal group (n = 30), acute ranked group (n = 12) and infection group (n = 10). were preoperative, postoperative day to detect the serum 1,5-IL-12P70, IL-4, IFN-? discretion that the concentration of 3 cytokines. data statistics using SPSS 15.0, P lt;0.05 was considered statistically significant, the use of analysis of variance and add the line LSD-t test and SNK-q to test the 3 groups, the concentration of 3 cytokines between groups, for the ROC curves, ROC area under the curve for computer processing (Az), to evaluate these three kinds of cytokines on the the diagnosis of acute rejection. [Results] three groups of patients before and after day 1 of serum IL-12P70, IFN-? discretion, IL-4 concentration and IFN-? discretionary / IL-4 were not statistically different; each group after 5 days of serum concentrations of IL-4 was no significant difference; ranked serum acute IL-12P70, IFN-? discretion concentration and IFN-? discretionary / IL-4 were significantly higher than the normal group and infected group; acute postoperative day 5 rows of serum IL-12P70, IFN-? discretion over the level of preoperative and postoperative day 1 was significantly increased (9.012 + - 0.736 vs 6.613 + - 0.598; 40.402 + - 13.414 vs 31.539 + - 13.323, P lt;0.05); IL-12P70, IFN-? discretion, IL-4, IFN-? discretionary / IL-4 in the first 5 days after the area under the ROC curve were 0.975,0.808,0.492,0.