Interferon α-2a and cimetidine combination therapy efficacy Rotavirus enteritis.docVIP

 PAGE \* MERGEFORMAT 7 Interferon α-2a and cimetidine combination therapy efficacy Rotavirus enteritis [Keywords:] @-2a Interferon cimetidine infants with rotavirus enteritis Rotavirus gastroenteritis in infants and young children common and frequently-occurring disease. It has no specific treatment, in order to explore effective methods of treatment in September 2004 ~ November 2005 during the epidemic of infantile diarrhea with combined interferon and cimetidine Treatment of 30 cases of infants with rotavirus enteritis compared with ribavirin to evaluate efficacy and adverse reactions. now report the results as follows. 1 Materials and Methods 1.1 General information on the prevalence of diarrhea during the period, all children with acute diarrhea, stool sample or egg drop soup is thin like water, no odor, with or without fever, vomiting, mild abdominal pain, micro-cough and other symptoms, had mild to signs of moderate dehydration, blood leukocytes is (7.0 ~ 12 × 109 / L, no specific changes in stool, microscope, fat globules, a few cases small quantity of white blood cells (lt;5/HP, fecal rotavirus antigen (RV Ag test (ELISA method was positive stool cultures were negative. meet the above criteria were a total of 60 patients, 30 patients were randomly divided into treatment group and control group of 30 patients. the two groups before treatment, age and duration, the difference was not statistically significant (Pgt; 0.5. 1.2 The diagnostic criteria by October 1993 lt;”China diagnosis and treatment of diarrheal disease programs (Revised Editiongt;gt; diagnostic criteria, selected patients were positive stool rotavirus antigen test. 1.3 in conventional rehydration therapy, correcting acid, based on microbial and other treatment, the treatment group received recombinant human interferon 60 000 u / (kg · d, intramuscular injection, 1 day for 3 days, cimetidine 10 ~ 15 mg / (kg · d, adding glucose infusion day 1, the control group were given r