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Itraconazole treatment of fungal esophagitis joint mosapride clinical observation
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Itraconazole treatment of fungal esophagitis joint mosapride clinical observation
[Abstract] Objective: To investigate the joint mosapride itraconazole on fungal esophagitis. Methods: 128 patients with smear by electronic endoscopy and pathological examination confirmed fungal esophagitis were randomly divided into two groups A group was given itraconazole United mosapride, B group was treated with clotrimazole, treatment 7 to 10 days. 10 days after treatment and smear repeated endoscopy. Results: A group cure rate of 97.1%, B group were cured rate of 71.7% cure rate difference between the two groups was statistically significant (P lt;0.05. Conclusion: Itraconazole treatment of joint mosapride is an effective method of fungal esophagitis.
[Keywords:] fungal esophagitis, itraconazole, mosapride
Fungal esophagitis is inflammation of the esophagus caused by fungal infection, the main pathogen Candida albicans, Candida albicans exists in nature, but also exists in all parts of the body, such as gastrointestinal, respiratory, urinary, reproductive system, is normal flora of the human body. In recent years due to extensive use of broad-spectrum antibiotics, corticosteroids, acid-suppressing agent multiple factors, so that the incidence of fungal esophagitis has increased to .2006 April April 2007 to accept our hospital 4 500 endoscopy patients, found 128 cases of fungal esophagitis, analysis of reports are as follows.
1 Subjects and methods
1.1 Object gastroenterology clinic and 128 patients hospitalized, 86 cases of males and 42 females, aged 40.3 + -10.5 years. Were randomly divided into two groups, A group of 68 cases, B group of 60 patients, two groups of gender, age difference not statistically significant (Pgt; 0.05.
1.2 The diagnostic criteria for esophageal mucosa was edema, hyperemia, erosions, ulcers, easy to touch the bleeding, mucosal surface covered with white spots or pseudomembranous, the brush smear visible hy
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