KMnO4-calcium indicator - Chemiluminescence Determination of Rhodamine B on the content of acetaminophen.docVIP

 PAGE \* MERGEFORMAT 14 KMnO4-calcium indicator - Chemiluminescence Determination of Rhodamine B on the content of acetaminophen Of: four-Juan Sun, Tang Xiao Shuang, Tang Yuhai, Xiongfeng Mei, Mooney grams Abdul hot hot wood, Wang Lijuan [Abstract] Objective To establish a rapid and accurate determination of acetaminophen by flow injection chemiluminescence method. Method under acidic conditions, KMnO4 oxidizable chemical luminescent calcium indicator, rhodamine B to this strong increase in light sensitivity of the presence of acetaminophen inhibition system of light, flow injection based on the establishment of a new determination of acetaminophen content chemiluminescence. results in optimal conditions, in 5.0 10-7-1.0 10 -5g/mL range of concentrations of acetaminophen reduced the CL signal are in good linear relationship between the detection limit (S / N = 3) is 7.0 10-8g/mL, of 1.0 10-6g/mL acetaminophen for 11 determinations, the relative standard deviation was 2.2%. Conclusion The method is simple, rapid, accurate, and for the tablet on the determination of acetaminophen, get more satisfaction results. [Keywords:] chemiluminescence, KMnO4, calcium indicator, rhodamine B, acetaminophen ABSTRACT: Objective To establish a rapid and precise continuous flow-injection chemiluminescence for the determination of paracetamol. Methods In acid solution, calcon could be oxidized by KMnO4 producing a weak chemiluminescence, and great chemilumimescence was obtained with the presence of rhodamine B. Then the signal was inhibited with the presence of paracetamol. The inhibitor intensity was linear with the concentration of paracetamol. Coupled with the flow injection technique, a rapid flow injection chemiluminescence method was developed for the determination of paracetamol. The parameters affecting the chemiluminescence signal were investigated. Results Under the optimized conditions, the linear range was 5.0 10-7-1.0 10-5g/mL. The detection limit wa