Laser irradiation combined with complex polysaccharide on tumor-bearing mice with tumor proliferation.docVIP

 PAGE \* MERGEFORMAT 11 Laser irradiation combined with complex polysaccharide on tumor-bearing mice with tumor proliferation [Abstract] Objective To study the low-energy laser irradiation combined with Solanum nigrum polysaccharide on the proliferation of mouse tumor bearing liver. The establishment of liver cancer in mice bearing subcutaneous growing tumor model, tumor-bearing mice were randomly divided into 5 groups for 10 consecutive days after the mice were killed. In situ hybridization detection of tumor vascular endothelial growth factor (VEGF) mRNA expression; immunohistochemistry to detect tumor tissue proliferating cell nuclear antigen Ki 67 expression. The results of low-energy laser irradiation combined with black nightshade polysaccharide can inhibit tumor cell proliferation and angiogenesis, significantly reduced VEGF mRNA, Ki 67 expression. Conclusion Low-energy laser irradiation combined with black nightshade polysaccharide can inhibit tumor cell proliferation and angiogenesis, inhibit tumor growth in mice bearing hepatocellular carcinoma. [Keywords:] low-energy laser irradiation; nigrum polysaccharide; proliferation Effects of laser irradiation solanum nigtum polysaccharide on tumor growth in cancer loaded mice [Abstract] Objective To study effects of low energy laser irradiation combined solanum nigtum polysaccarides on tumor growth in liver cancer loaded mice.Methods Established liver cancer loaded mouse model and divided randomly mice into five groups.n calculated the tumor inhibitory rate and spleen index. We detected the expression of VEGF mRNA by in situ hybridization and Ki 67 protein by immune histochemistry.Results Low energy laser irradiation combined solanum nigtum polysaccharide could inhibit tumor growth and angiogenesis, the expression of VEGFmRNA, Ki 67 protein were decreased.Conclusion Low energy laser irradiation combined solanum nigtum polysaccharide can obviously inhibit the proliferation of liver ca