Late-onset vitamin K deficiency bleeding in 50 cases.docVIP

 PAGE \* MERGEFORMAT 12 Late-onset vitamin K deficiency bleeding in 50 cases [Abstract] Objective To study late onset vitamin K deficiency bleeding in the clinical features and the need for preventive intervention. Methods From August 2002 ~ December 2007 admitted 50 patients with late onset vitamin K deficiency bleeding cases were reviewed . Results men than women, both exclusive breastfeeding, 98% of the children after birth did not receive vitamin K to prevent disease, 66.0% of the children without any inducement, sudden and abrupt anemia, bleeding tendency, PT, APTT was prolonged , 70.0% had intracranial hemorrhage, CT examination for a wide range of intracranial hemorrhage, subdural hematoma with subarachnoid hemorrhage, cerebral hemorrhage more common. intracranial hemorrhage and poor prognosis, the mortality rate 54.3%, improved in, have different degree of brain injury sequelae. Conclusions Late-onset vitamin K deficiency bleeding intracranial hemorrhage rate, high mortality and morbidity, the prognosis is poor, must be prevention. [Keywords:] vitamin K deficiency, intracranial hemorrhage, intervention Late-onset vitamin K deficiency bleeding (VKDB65% ~ 100% intracranial hemorrhage [1], the rapid onset of disease, mortality and disability is high, serious harm to child health, prevention is essential, this will be our department in 2002 years 8 months to December 2007 patients admitted As follows. 1 Materials and Methods 1.1 General Information August 2002 ~ December 2007 50 cases of children admitted to our department, 36 males and 14 females, male to female ratio was 2.5:1, rural 39, urban 11 patients, aged from 12 to 90 days of which 12 to 28 days in 6 cases, 37 cases from 29 to 60 days, 61 to 90 days in 7 cases. All the patients denied family history of bleeding disorders. diagnostic criteria [1]: (1 breastfeeding children, (2, 2 weeks after birth 3 months sudden onset, (3 acute or subacute intracranial hemorrhage (lumbar puncture,