Laparoscopic CO2 pneumoperitoneum on intraperitoneal growth of ovarian cancer in nude mice and diffusion of.docVIP

 PAGE \* MERGEFORMAT 10 Laparoscopic CO2 pneumoperitoneum on intraperitoneal growth of ovarian cancer in nude mice and diffusion of Study: Left million Xing, Tanglong Ying, Chen Qizhen, Wu Zaixin [Abstract] Objective laparoscopic CO2 pneumoperitoneum on intraperitoneal growth of ovarian cancer in nude mice and diffusion. Methods 50 nude mice by intraperitoneal injection of ovarian cancer HO-8910 cells, 14 days after surgery according to different requirements of the following groups: ( a control group (GA, only the delivery of anesthesia, (2 laparotomy group (ML, pubic symphysis is about 2 cm midline incision into the abdomen, intestines and other organs will be set aside out of salt in a sterile gauze, the operation lasted 1 h, ( 3 balloon group (GL, built 14 Forley peritoneal catheter 1, inflatable abdominal swelling continues after 1 h, (4CO2 pneumoperitoneum group (CO2L, xiphoid pneumoperitoneum needle into the abdomen under the charge into CO2, the pressure to maintain In the 2 mm Hg, sustained injection 1 h, (5He pneumoperitoneum group (HeL, surgical steps are the same CO2 pneumoperitoneum, only the injected gas is He. slaughtered animals 4 weeks after surgery observed experimental results. The results of tumor foci in nude mice HO-8910 mainly in the abdominal wall and intestinal wall, and liver, diaphragm and omentum is rarely found, and no significant difference among the groups. In addition the tumor volume in each group is almost no difference. Conclusion with open surgery, He pneumoperitoneum comparison, CO2 pneumoperitoneum on intraperitoneal ovarian cancer growth and spread of extremely small, while the gas-free advantages of laparoscopic surgery has yet to be confirmed by further experiments. [Keywords:] Laparoscopy, CO2 pneumoperitoneum, ovarian cancer, nude mice [Abstract] Objective To evaluate the impact of CO2 pneumoperitoneum on ovarian cancer peritoneal growth and spread in rats.Methods 50 nude rats were submitted to intraperiton