Korean newborn umbilical cord blood hemoglobin γ -chain related research.docVIP

 PAGE \* MERGEFORMAT 7 Korean newborn umbilical cord blood hemoglobin γ -chain related research [Abstract] Determination of umbilical cord blood hemoglobin in the Korean γ G136 / (γ G136 γ A136) ratio, and analysis of its significance. [Methods] hemoglobin solution chain, polyacrylamide gel electrophoresis separation and electrophoretic determination of optical density of 160 cases of Yanbian Korean umbilical cord blood hemoglobin in γ G136 / (γ G136 + γ A136) ratio. [Results] one cases (0.63%) γ G136 / (γ G136 + γ A136) ratio of 20% ~ 48% range; the remaining 159 cases (99.37%) ratio at 50% ~ 80% range, with an average ratio of 66.40% ± 3.90%. [Conclusion] Korean newborn hemoglobin γ G136 / (γ G136 γ A136) ratio and other domestic inter-ethnic differences. [Keywords:] gene newborn babies who Stocks ABSTRACT: OBJECTIVETo determine γ G136/γ A136 ratio in haemoglobin (Hb) of cord blood of Korean  Chinese neonates, Yabina, and to discuss its clinical significanse.METHODSHb chain were separated by modified method of Rovera and PAGE, and the quantitation of globin chain composition was scaned by BioSpectrum (r) AC Imaging Systerm of UVP in 160 cases of Korean  Chinese neonates.RESULTSThe ratio in one case (0.63%) was under 20% ~ 48%, and in 159 cases (99.37%) were under 50 ~ 80%, average ratio was 66.40% ± 3.90%. CONCLUSIONThe Hb (γ G136/γ A136) ratio of core blood of Korean  Chinese neonates, Yanbian, is difference than other nationalities. Keywords:: genes; infant, newborn; ethnic groups There are two types of fetal hemoglobin γ -chain, namely, γ G136 and γ A136, by γ G, γ A2 a non-alleles are expressed. Newborns at birth γ G136/γ A136 ratio 7:3,6 months later to reach adults (4: 6) levels. known γ G, γ A-chain exists in all populations, while some newborns γ G136/γ A136 were significantly higher or lower than 7:3, genome analysis found that these neonates are often γ chain gene abnormalities [ 1,2]. In addition, some groups of people and ethnic γ c