Keratoacanthoma one cases of malignant diagnosis of Experience.docVIP

 PAGE \* MERGEFORMAT 8 Keratoacanthoma one cases of malignant diagnosis of Experience Keratoacanthoma is a benign skin lesions. A result of self-limiting, no treatment can also choose to do partial surgical resection, but few cases have malignant, should rise to clinical attention. In our hospital in August 2000 ~ August 2004, a total of pathological diagnosis of keratoacanthoma 54 patients, of which 1 case was malignant Keratoacanthoma, now that the cases reported as follows and make. A medical summary of Patients, male, 56 years old, farmers, found that an uplift of the left cheek a small nodule 3 years without any symptoms. Out-patient surgical resection. Biopsy Specimens, see: spindle organization with a part of the skin, the skin see a lung tumor of the size of 2cm × 2cm, higher than the leather 0.5cm, tumor Chuo-ku, see a volcano-like cracks, containing a small amount of white loose, fine granular necrotic material, on both sides of the skin was light red and dark red lip-shaped bulge. Endoscopic See: exogenous epidermal cell proliferation, was obviously lip-shaped uplift, two lips can be seen clearly Chuo-ku, keratosis, basal side of epidermal cells flattened, eosinophilic, and glass-like degeneration, and see the obvious inflammatory cell infiltration, expressed as self-limiting lesion characteristics; the other side of the base near the cutting edge (and therefore fail to understand the proliferation of epithelial cells), an enclosed keratosis beads, special treatment for epidermal growth active, but the base is still intact, no invasive growth of the phenomenon of . Pathological diagnosis: Keratoacanthoma.术后18Months, the patient again, see the original surgical incision at the side of the skin showed small nodular bulge. Biopsy, see: Local damage to the epidermis to the dermis depression, the depression filled with keratinized material, the base down to the bottom of the invasive growth of cells, showing that cells in hyperkera