Levamlodipine Metoprolol clinical observation of treatment of moderate hypertension_0.docVIP

 PAGE \* MERGEFORMAT 9 Levamlodipine Metoprolol clinical observation of treatment of moderate hypertension On: Su Hao Ran, Fu Wentao, Wu Kaiyou, MO Chuqing [Abstract] Objective To compare the combined application of L amlodipine and metoprolol and amlodipine alone L-moderate hypertension on antihypertensive efficacy and safety. Methods 172 patients with moderate hypertension in patients with primary given Levamlodipine 2.5mg / times, day 1, after 4 weeks of treatment selected target blood pressure less than 80 patients were randomly divided into A, B group, 40 patients in each group, A group in the original amlodipine with L-add services on the basis of metoprolol 12.5 ~ 25.0mg, 2 times a day, B L amlodipine group will increase as the dose of 5mg, day 1, were observed after 8 weeks treatment antihypertensive effect and the impact on heart rate, adverse reaction rates. Results A group of effective blood pressure and adverse reaction rates were 92.50%, 12.50%, B group were 72.50%, 22.50%, A group of adverse reaction rates significantly lower than the B group. Conclusion L amlodipine synergistic antihypertensive effect of metoprolol to reduce the adverse reactions and to overcome the Levamlodipine faster heart rate. [Keywords:] L-amlodipine, metoprolol, high blood pressure Hypertension is the most common cardiovascular disease, the incidence increased year by year, can cause high blood pressure and progress of ongoing systemic small artery disease, the blood vessel wall remodeling, continued progress will lead to target organs such as heart, brain, kidney ischemic injury. At the same time high blood pressure can promote the formation of atherosclerosis and development. Levamlodipine acid and metoprolol as first-line clinical treatment of hypertension drugs, when used alone, there are some deficiencies. The author Forward-looking randomized controlled clinical trials, their combined use in moderate essential hypertension, and achieved better clinical re