Liquorice water extract of smoking in mice lung tissue superoxide dismutase and malondialdehyde of.docVIP

 PAGE \* MERGEFORMAT 20 Liquorice water extract of smoking in mice lung tissue superoxide dismutase and malondialdehyde of 【Abstract】 Objective To observe the water extract of liquorice on smoking in mice lung tissue superoxide dismutase (SOD) and malondialdehyde (MDA) effects. Methods Kunming mice were randomly divided into three groups, namely normal control group, smoking and model group, licorice water extract group. The normal control group, mice do not smoke, the other two groups of consecutive non-smoking 60 d, 4 times / d, 30 min / times, licorice water extract group 2 times / d given distilled water control, 60 d after the animals were killed, whichever left lung fixed, paraffin-embedded, sliced HE staining and the remaining lung tissue homogenate made to detect SOD activity in lung tissue, MDA levels. Results smoking group programs, ranging from mice lungs appeared chronic bronchitis and emphysema, lung SOD activity was significantly decreased at the same time, MDA content increased significantly. Add clothes after smoking a water extract of liquorice pulmonary pathological features of mice significantly reduced lung SOD activity increased, MDA content decreased. Conclusion licorice water extract in mice caused by long-term smoking bronchopulmonary histopathological damage have a protective effect, its mechanism may be related to licorice to play in the lungs and other relevant anti-oxidation. Keywords: water extract of licorice root; smoking; lung tissue; superoxide dismutase; malondialdehyde The Protective Effects of Glyrrhizae on Smoking induced Pulmonary Injury in Mice Abstract: ObjectiveTo investigate the protective effects of glycyrrhizae water-extraction on smoking-induced pulmonary injury in mice.MethodsKuming mice were randomly divided into 3 groups: healthy control group, model group and glycyrrhizae group. Except healthy control group, the others were exposed to cigarette smoke, qid, 30 minute / day for 60 days.