药物代谢动力学-陈季强.pptVIP

浙江大学医学院 陈季强教授 Email: chenjq@zju.edu.cn;Chapter 2. Pharmacokinetics;Chapter 2. Pharmacokinetics; Chapter 2 Pharmacokinetics ;Part 1. Transport of drug across cell membrane(药物的跨膜转运);Part 1. Transport of drug across cell membrane;Part 1. Transport of drug across cell membrane; ①Absorption(吸收); ②Distribution(分布); ③Biotransformation(生物转化), or Metabolism(代谢); ④Excretion(排泄). ①, ②, and ④: Transport(转运); ③ and ④: Elimination(消除). ;2. The patterns of drug transport across cell membrane(药物跨膜转运类型):; ▲Filtration(滤过) —— along pressure gradient. ▲Simple diffusion(简单扩散)