6种方案治疗早期梅毒的成本-效果分析.pdfVIP

6 种方案治疗早期梅毒的成本一效果分析 周波林 l 飞胡蔚毅 2 (1.广西北海市人民医院，北海市 536000;2. 上海市皮肤性病医院，上海市 200020) 中团分类号 R956jR986 文献标识码 C 文章编号 1001 … 0408(2007)23… 1773一 02 摘 要 目的:评价 6 种方案治疗早期格悉的经济效果。方法:将 1516 例早期梅森患者随机分为 4争夺卡阁青霉素、头抱曲松纳、爷 盖骨霉素、阿奇霉素、米诺环索、多西坏索 6 组，运用药物经济学方法分析其成本…效泉。结果: 6 种方案药品成本分别为 36.8 、 5 1. 8 、 37.9 、 18.3 、 180.9 、 47.6 元，平均有效率分别为 93.35% 、 90.13% 、 88.36% 、 68 嗣 54% 、 87.38% 、 87.88% j 在阿奇霉素方案的基 础上，每 J导获 1 个单位效来，方案普鲁卡因青霉素、头抱佛松钧、爷皇帝霉素、米诺坏索、多西坏余所需追加的成本分别为 74.57 、 155.16 、 98.89 、 863.06 、 151.50 元。结论:普鲁卡因青霉素方案较位。 关键词 早期梅毒;用药方案;成本…效果分析 Six Therapeutic Regimens for Early Syphilis: Cost - Effectiveness Analysis ZHOU Bolin(Guangxi Beihai Peoples Hospital,Beihai 536000,China) HU Weiyi(Shanghai Hospital of Dermatology and Venereology,Shanghai 200020,China) ABSTRACT OB]ECTIVE: 丁o evaluate the cost …effectiveness of six therapeutic regimens for early syphilis. METHODS: A total of 1 516 patients with early syphilis were randomly divided into 6 groups: procaine peniciJlin group , ceftriaxone sodium group , benzathin 巳 benzylpenicillin group , azi thromvein group , minocyeline group and doxycycline group. 丁he cost … effective翩 ness of the 6 groups was compared using the method in pharmacoeconomics.RESULTS:The costs for the 6 schemes were 36.8 yuan , 51.8 yuan , 37.9 yuan , 18.3 yuan , 180.9 yuan and 47.6yuan, respectively; the average effective rates were 93.35% , 90.13% ,88.36% ,68.54% ,87.38% and 87.88% , respectively;on the basis of azithromvein group , the incremental costs for ev? éry one unit increment of effectiveness for procaine penicillin group , ceftriaxone sodium group , benzathine benzylpenicillin group , minocyeline group and.doxycyc;line group were 74.57 yuan , 155.16 yuan , 98. 89yuan, 863.06 yuan and 151. 50yuan , re? spectively. CONCLUSION: Procai