Mixture of anti lobular hyperplasia of breast lobular hyperplasia of rats.doc

 PAGE \* MERGEFORMAT 11 Mixture of anti lobular hyperplasia of breast lobular hyperplasia of rats [Abstract] Objective To observe the anti-lobular hyperplasia of mammary glands mixture on the treatment of animal models. Methods intramuscular progesterone, estradiol benzoate combined method of rat mammary gland hyperplasia, lobular hyperplasia with a mixture of anti 30.0,15.0, 7.5ml/kg 3 doses for 30 days, determination of rat papillary diameter, generally observed morphological changes of the nipple and breast tissue changes under the microscope to observe the influence of blood rheology, serum levels of estradiol benzoate. Results of anti lobular mixture can be significantly reduced proliferation of rat papillary hyperplasia of the diameter, reducing the number of breast lobules, acini and acinar lumen diameter number and improve the hemorheological parameters, significantly reduce the symptoms of nipple morphology and reduce serum levels of estradiol benzoate. Conclusion mixture of anti-estrogen lobular hyperplasia induced rat mammary glands has a good effect. [Keywords:] mixture of anti-proliferation of breast lobular hyperplasia in rats estrogen Abstract: Objective To observe the effect of Kangruxianxiaoyezengsheng on rats with mastoplasia. Methods After benzoate estradiol and progestogen had been injected into rats, the mastoplasia models were produced. The model rats were treated with Kangruxianxiaoyezengsheng (30.0, 15.0, 7.5ml/kg) for 30 days, the mammary papilla diameter of the rats in all groups were measured, morphologic changes of mammary papilla and the changes of mammary gland were observed under microscope, the content of estradiol in blood serum and blood rheology were determined by radio-immunity. Results Kangruxianxiaoyezengsheng could significantly shrink the mammary papilla’s diameter of the mastoplasia rats, lessen mammary papilla’s symptoms in morphology, reduce the quantity of lobule of mammary gland, lobule-alveolus in mammary g