- 1、本文档共7页,可阅读全部内容。
- 2、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
- 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
查看更多
Nanoemulsion capsaicin injection of hemolytic and vascular irritation test
PAGE \* MERGEFORMAT 7
Nanoemulsion capsaicin injection of hemolytic and vascular irritation test
[Abstract] Objective nanoemulsion capsaicin injection for evaluation of hemolytic and vascular stimulation. Methods of rabbits in vitro hemolysis test and vascular irritation test in rabbits. Results of 0.004% capsaicin injection nanoemulsion is no hemolysis, and 3 h No red blood cell agglutination by 20 g / kg rabbit ear vein injection of non-vascular stimulation. Conclusion of effective dose of capsaicin injection nanoemulsion no hemolysis and vascular irritation, provide reference for further research.
[Keywords:] Capsaicin; nanoemulsion; injection; hemolytic; vascular stimulation
Abstract: Objective To evaluate the hemolysis and vascular irritation of nanoemulsion Injection of capsaicin.Methods Experiments including in vitro hemolytic test in rabbits and in vivo vascular irritation test in rabbits were carried out.Results Hemolysis and erythrocyte agglutination were not observed in in vitro test after adding 0.004% capsaicin nanoemulsion for 3 hours. Vascular irritation in rabbits was not observed also after intravenous administration of the preparation at the dosage of 20 g / kg.Conclusion There was no hemolysis and vascular irritation reactions concerned with nanoemulsion injection of capsaicin at the effective dosage in rabbits.
Keywords:: capsaicin; nanoemulsion; injection; hemolysis; vascular irritation
Capsaicin (capsaicin) [1] is material and has a spicy chili major component of drug activity, through the selective antagonist of neuropeptide substance P exert anti-inflammatory analgesic effect [2], can be effective in treating postherpetic neuralgia, diabetic neuropathic pain, rheumatoid arthritis and osteoarthritis, pain, is a new non-addictive anti-inflammatory analgesic drugs [3]. As is effective and the United States Pharmacopoeia began to collect the set from the 24 version. nanoemulsion is made to capsaicin injection, to achieve rapi
您可能关注的文档
- Myocardial protective effect of isoflurane mechanisms and clinical application.doc
- Myocardin the phenotype of vascular smooth muscle cells in the mechanism of transformation.doc
- Myocardial protection after adaptation Progress.doc
- Myocarditis complicated with cardiogenic shock condition observation and nursing care.doc
- Myocardial protection and application of clinical research advances.doc
- Myocardial tissue in mice induced lysis supernatant of mouse myeloma Sp2 - 0 cells.doc
- Myocarditis one cases of severe brain.doc
- Myocardium of diabetic rats with platelet-derived growth factorB expression and cardiac fibrosis.doc
- Myomectomy surgery report of 46 cases.doc
- Myocardial ischemia - reperfusion no-reflow mechanism and medical thinking in the_0.doc
- 2025年诺华制药创新药物研发项目管理团队协作机制报告.docx
- 2025年无人机蜂群军事侦察与民用公共安全监控应用研究报告.docx
- 数字音乐版权保护与运营2025年技术壁垒与突破策略报告.docx
- 2025年快消品行业数字化营销法规与合规报告.docx
- 智慧社区建设2025年市场需求与产业发展趋势预测研究报告.docx
- 乡村振兴中的农业科技与农村电商市场拓展策略研究.docx
- 2025年国防军工企业数字化转型与国防科技工业数字化转型路径优化与效果评估报告.docx
- 2025年自动驾驶出租车(Robotaxi)商业模式下的车载娱乐系统与增值服务研究.docx
- 康复医疗行业发展趋势报告:国产设备替代市场潜力与挑战应对策略分析.docx
- 2025年二手交易平台商业模式创新与市场监管的消费者权益保护法律风险预警报告.docx
文档评论(0)