Nano-materials in the polymerase chain reaction progress in the application of.doc

 PAGE \* MERGEFORMAT 34 Nano-materials in the polymerase chain reaction progress in the application of Study: Zhuo Li Qiao Guangming Lin Tang Bo [Abstract] polymerase chain reaction (PCR technology is the core technology of modern molecular biology to study ways to improve the efficiency of PCR amplification is important. The traditional method of improving the efficiency of PCR amplification with more limitations, making the PCR extension growth can not achieve the desired results. With the development of nanotechnology, nanomaterials have special surface effect and size effect, surface modification can be a variety of easy and Macromolecular protein, nucleic acid interactions, the structure of biological molecules special effects and function. study of nanomaterials to improve the efficiency of PCR amplification techniques and methods, has a very important theoretical significance and application value. This article references 41, reviewed the recent system of nano-materials in the application of PCR the status quo and prospect of nano-materials for future application in the PCR system and its development prospects. [Keywords:] polymerase chain reaction, nano-materials, specificity, amplification efficiency, review Application Progresses of Nanomaterials on Polymerase Chain ReactionLI Na, QIAO Guang-Ming, ZHUO Lin-Hai, TANG Bo * (College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Engineering Research Center of Pesticide and Medicine Intermediate Clean Production, Ministry of Education, Shandong Normal University, Jinan 250014) Abstract Polymerase chain reaction possesses very important academic and application meanings to study the ways and technologies of improving the efficiency of PCR based on nanomaterials.In this review, recent application status of nanomaterials on PCR was summarized with 41 references.Particularly, the developing trends and prospects in the f