Nerve growth factor in the high altitude environment and non-contusion contusion different expression of retinal.doc

 PAGE \* MERGEFORMAT 15 Nerve growth factor in the high altitude environment and non-contusion contusion different expression of retinal Of: Jing Liu United States, Yanzhen Guo, Qin Pingying [Abstract] Objective To observe the nerve growth factor (nerve growth factor, NGF) in the high altitude environment retinal contusion contusion over the same period with non-expression levels are different. Methods The experimental animals under the plateau into two groups, one group of eye contusion group , a group of non-contusion group, were drawn on days 1,3,7,14, 40 g / L paraformaldehyde, paraffin embedded sections, immunohistochemistry NGF, NGF expression in the two groups over the same period the level of retinal different. Results NGF in the high altitude environment of rabbit retina after eye contusion expression levels at each time point with the same period in the retina of non-blunt expression levels of NGF in the differences (125.82 + -1.30 vs. 124.51 + -0.56,117.49 + -1.08 vs . 120.39 + -0.87,121.05 + -0.77 vs. 118.80 + -0.78,126.45 + -0.79 vs. 124.36 + -1.25, P lt;0.05), expression pattern of the two groups is not the same. Conclusion altitude hypoxia and high altitude environment The eye contusion affect both the expression of NGF level of the retina. [Keywords:] nerve growth factor; retina; Plateau [Abstract] Objective To investigate the different expressions of NGF in the rabbits, contused and non-contused retina in high altitude environment.Methods Divided the animals in high altitude environment to two groups: one was contused eyes and the other was non-contused, and the eyes were got at 1 d, 3 d, 7 d and 14 d respectively.Meanwhile, paraffin retina slices were made and the expressions of NGF in the retinas were tested with immunohistochemistry, to compare the expressions of NGF in the rabbits, contused and non-contused retina in high altitude environment.Results The expression of NGF in the contused retina was different from non-contused re