Nervous system immune and skin relationship.doc

 PAGE \* MERGEFORMAT 20 Nervous system immune and skin relationship Abstract: The nerve fibers in the skin secretion of neurotransmitters, expression neurohormone; skin cells can also secrete neurotransmitters and neural hormone receptor expression. These substances can regulate cell function in the epidermis and dermis. Within a short period of time exists in the skin of immune cells (ie: macrophages and lymphocytes) from receptor-regulated neurotransmitters. Skin diseases, especially inflammatory reactions to the skin immune system becomes unstable nervous, especially typical of psoriasis. Such instability may be secondary may also be induced by the inflammatory process and the maintenance due. Nervous system, immune and skin interact closely linked. This paper presents a new concept: nervous skin immune system. Nervous, immune and skin system (NICS) in anatomy, biology, and certain pathological processes in close contact and interaction. There are physical, chemical and functional links. This paper will describe the skin neurotransmitters, nerve growth factor (NGF) and neuronal features such as skin cells produce the neurotransmitter receptor expression, as well as to discuss the skin cells and neurons, the physical and functional inter-relationships and the concept of skin pathology in the NICS the problem. Skin neurotransmitters and growth factors In numerous neurotransmitters and neural hormones, it has been proven in the skin of about 20 species, most of neuropeptides, namely substance P, neuropeptide Y, vasoactive intestinal peptide (VIP), peptide histidine isoleucine , Growth Hormone Inhibin, neurotensin, gastrin-releasing peptide moderate kinin. Other hormones, such as the nervous prolactin, MSH (MSH), adrenocorticotropic hormone (ACTH), or catecholamines, enkephalins, endorphins, or acetylcholine. The number of skin changes in neurotransmitter depends on the individual, disease, and location. The