Obesity and type 2 diabetes plasma visfatin levels and insulin sensitivity.doc

 PAGE \* MERGEFORMAT 12 Obesity and type 2 diabetes plasma visfatin levels and insulin sensitivity Of: Jiang Rong, Liu Xiaoying, LIU Li Bin, Chen Xiaochun [Abstract] Objective To investigate patients with obesity and type 2 diabetes and its levels in plasma visfatin and insulin sensitivity. Methods to set the normal body weight without diabetes group (11 patients, the obese group (10 cases, type 2 diabetes, non- obese group (16 cases, type 2 diabetes obese group (9 cases were detected by enzyme immunoassay in plasma visfatin concentration and insulin resistance index assessed insulin sensitivity of plasma visfatin levels and anthropometric indices and metabolic parameters of relevance. Results Fasting Plasma visfatin levels in normal weight, obesity and type 2 diabetes patients with no significant differences (Pgt; 0.05, plasma visfatin levels were positively correlated with fasting blood glucose (r = 0.336, P = 0.0226), no correlation with insulin resistance , waist circumference, waist-hip ratio, high density lipoprotein cholesterol in plasma visfatin concentrations were independently associated (P = 0.03,0.041,0.006. Conclusion normal weight, obesity and type 2 diabetes patients with fasting plasma visfatin levels were similar, visfatin and closely related to glucose and lipid metabolism may be related to insulin resistance independent of plasma visfatin concentration can not be used as the clinical diagnosis of obesity or diabetes indicators. [Keywords:] obesity, diabetes, type 2, cytokines, lipid cells, the body mass index, insulin Department of visfatin is a new discovery in the main by the visceral adipose tissue fat cells secrete a factor, can bind to and activate the insulin receptor, insulin-like effect of simulation, thereby reducing blood sugar, but also can promote the differentiation of adipose tissue, synthesis and accumulation [1] . The author of normal weight, obesity and type 2 diabetes patients visfatin concentration and anthropom