Obesity leading to insulin resistance in type 2 diabetes mellitus Mechanism and Countermeasures.doc

 PAGE \* MERGEFORMAT 16 Obesity leading to insulin resistance in type 2 diabetes mellitus Mechanism and Countermeasures [Keywords:] Obesity Abstract: In recent years, domestic and foreign literature, an overview of obesity, insulin resistance and type 2 diabetes mellitus causing a major factor in its mechanism and the basic countermeasures. With a view to obesity lead to insulin resistance in type 2 diabetes, the main factors and their role in the mechanism of a more systematic understanding of type 2 diabetes and its complications the role of prevention and treatment guidance. Keywords:: obesity; 2 diabetes mellitus; insulin resistance; mechanism At present, obesity and diabetes has become a common disease, both closely related, often associated with lipid metabolism disorders and insulin resistance (Insulin resistant, IR) co-exist. With economic development, lifestyle changes and age, China’s incidence of obesity and diabetes are increasing year by year, in recent years, many studies found that diabetes significantly increased blood lipids, and more associated with abnormal blood rheology and blood condensate increases [1,2]. Lipid metabolism disorders leading to obesity, IR is a precursor of type 2 diabetes, the performance of its result, diabetes, and increase, seriously affecting the body’s health and life expectancy, so obesity and insulin resistance in type 2 diabetes to explore the relationship has aroused widespread concern and attention and seek effective methods to prevent type 2 diabetes the generation and development, and urged the rehabilitation of diabetics. In this paper, leading to obesity, insulin resistance and type 2 diabetes a major factor in its mechanism and the basic countermeasures. 1 IR throughout the entire process of type 2 diabetes mellitus IR refers to the normal dose of insulin produces a state of normal biological effects, that is, the target tissue insulin sensitivity to insulin and (or) reactive shown to reduce the pathol