On drug treatment of hypertrophic cardiomyopathy.docVIP

On drug treatment of hypertrophic cardiomyopathy Abstract] hypertrophic cardiomyopathy (hypertrophic cardiomyopathy, HCM) is a non-symmetry of myocardial, characterized by uneven hypertrophy, unexplained heart disease. Septal hypertrophy were much higher than the typical free wall significantly, causing left ventricular outflow tract obstruction, it is also known as primary hypertrophic subaortic stenosis (IHSS). occasionally concentric hypertrophy was the South, not with obstruction, but also apical hypertrophy, called apical hypertrophic cardiomyopathy, the disease-oriented subtypes. Widely distributed in the world, the family disease more often arrhythmia and early sudden death can occur. [Keywords:] drug treatment of hypertrophic cardiomyopathy HCM patients under different hemodynamic characteristics, the appropriate medication. For patients with significant ventricular hypertrophy, even if asymptomatic, should also be given drug therapy to improve diastolic ventricular filling and myocardial ischemia and delayed the appearance of symptoms, obvious on the asymptomatic left ventricular outflow tract pressure gradient in children and young people can also be given to preventive medicine; of asymptomatic non-obstructive HCM patients, drug therapy is a good Italian style Sun. (1) β-blocker drugs for the molten treatment of this disease for almost 30 years. Has the following functions: ① slow down the faster the heart rate during exercise, ② to reduce ventricular outflow tract pressure gradient, ③ reduced myocardial oxygen consumption, alleviate symptoms of angina, ④ increased left ventricular filling, ⑤ have anti-arrhythmic effects, ⑥ reduce left ventricular work to ease the progression of the disease. This is the responsibility through its inotropic effect and make the nervous system and catecholamine inhibition. The drug is widely used in obstructive non-obstructive HCM patients with symptomatic heart selective who were as effectiv