On obesity and insulin resistance and leptin resistance in the interaction.docVIP

 PAGE \* MERGEFORMAT 12 On obesity and insulin resistance and leptin resistance in the interaction [Abstract] of fat cell proliferation, differentiation disorders can cause excessive accumulation of fat tissue, and then lead to obesity, obesity is not a single gene disorders, genetic and nutritional factors and behavior caused by the interaction of multiple factors such as a nutritional imbalance, obesity occurrence caused by a range of nutritional diseases. leptin resistance and insulin resistance in closely related, and coronary heart disease, hypertension, type 2 diabetes, hyperlipidemia, and many other common risk factors for serious diseases. In recent years, fat cell differentiation and development of the molecular regulation of their association with obesity, insulin resistance, the relationship between the pathogenesis of international research has been a hot spot. Keywords:] leptin resistance in obesity, insulin resistance Obesity not only affects the body, more importantly, it often with type 2 diabetes, hypertension, high cholesterol and even some cancer-related, as it is difficult to solve medical problems, now obesity and insulin resistance and leptin resistance in doing a Simple Survey. 1 obesity and insulin resistance (IR 1.1 fat cell differentiation and insulin resistance Fat cell differentiation and regulation of energy metabolism and body weight is important to maintain a balanced relationship between the disorder of the regulation process in the pathogenesis of obesity may be one of the links. Insulin resistance is the role of insulin target organs, tissues such as liver, muscle and adipose tissue biological effects of insulin reduction or loss of reactivity, resulting in a series of pathophysiological changes and clinical manifestations [1]. is by fat cells, insulin receptor or the receptor caused by abnormal structure or expression of the pathophysiological process. from clinical observation known, and fat cell dif