On the diabetic foot with different syndromes of vascular proliferation associated nuclear antigen (Ki67) expression of Difference.docVIP

 PAGE \* MERGEFORMAT 6 On the diabetic foot with different syndromes of vascular proliferation associated nuclear antigen (Ki67) expression of Difference Paper Keywords diabetic foot TCM syndrome of the posterior tibial artery nuclear proliferation-related antigen clinical research Abstract Objective: To explore the diabetic foot syndrome differentiation type and vascular proliferation associated nuclear antigen expression differences. Methods: 32 patients with diabetic foot amputation according to TCM is divided into qi and blood deficiency Stagnation Syndrome, context stasis hot card, drug card and Qi and Yin Deficiency Heat context Stagnation Syndrome, respectively, amputation of their limbs posterior tibial artery Application immunohistochemical staining for proliferating cell nuclear antigen (Ki67) expression of observation and analysis. Results: Ki67 positive expression of the degree of diabetic foot arteriosclerosis obliterans was negatively correlated with the degree of vascular inflammatory lesions was positively correlated. Conclusion: The inflammation in diabetic macrovascular disease, the process has played an important role. Diabetes to foot is a serious complication of diabetes, according to statistics in 1996 the world’s 120 million diabetics is expected by 2025 will reach 250 million more, about 15% of diabetes patients will in their lives a certain the time of foot ulcers or gangrene [1]. At present, for etiology and pathogenesis of diabetic foot, while not entirely clear, but we recognized diabetic macrovascular disease leading to atherosclerosis is the most important factor in the pathogenesis of diabetic foot. Now in October 2004 ~ May 2005 we have treated 32 cases between diabetic foot amputation in patients with arterial vascular specimens proliferating cell nuclear antigen (Ki67) and its sub-types of TCM-related research reported as follows. A clinical data 1.1 General information: 32 cases of metabolic diseases are the Tianjin Med