Paroxetine treatment of obsessive-compulsive disorder risperidone combined control study.doc

 PAGE \* MERGEFORMAT 9 Paroxetine treatment of obsessive-compulsive disorder risperidone combined control study Of: Li Xu, Rui Gao Hong Wang Yan Mei Wang Erfang [Abstract] Objective To investigate the treatment of paroxetine in obsessive-compulsive disorder combined risperidone efficacy and safety. Methods 42 patients with OCD were randomly divided into two groups of the 21 cases, the joint study group paroxetine oral risperidone in the control group clomipramine treatment alone was observed in 10 w. 10 w before treatment and treatment of obsessive-compulsive disorder by the end of Inventory, Hamilton Anxiety Scale, Hamilton depression rating scale efficacy, adverse side effects rating scale. Results 10 w end of the study group cure rate was 33.33%, effective rate is 80.95%, total effective rate was 100% in the control group were 19.05%, 33.33%, 95.23%, a significant effect of group than the control group (2 = 4.13, P lt;0.05. The treatment of 10 w scale scores than the end of the two groups before treatment was significantly decreased (P all lt;0.01, but the study group was significantly decreased compared with the control group (P all lt;0.05. Conclusion Paroxetine joint interest effective treatment of obsessive training ketone significantly better than single treatment with clomipramine, and safe, and better compliance. [Keywords:] obsessive-compulsive disorder paroxetine clomipramine risperidone [Abstract] Objective To explore the clinical efficacy and safety of paroxetine combining with risperldone in the treatment of obsessive compulsive disorder (OCD). Methods 42 patients with OCD were randomly divided into research group (n = 21) receiving paroxetine plus risperldone and control ( n = 21) doing single paroxetine for 10 weeks. Clinical efficacies were assessed with the Yale Brown Obsessive Compulsive Scale (Y BOCS), Hamilton Anxiety Scale (HAMA) and Hamilton Depression Scale (HAMD) and adverse reactions with the Treatment Emergent Symptom Sca