Pathological examination of Streptococcus pneumoniae pneumonia.docVIP

 PAGE \* MERGEFORMAT 10 Pathological examination of Streptococcus pneumoniae pneumonia [Abstract] pneumococcal pneumonia by Streptococcus pneumoniae (or pneumococcus, streptococcus pneumoniae, streptococcal pneulnoniae) induced acute lung inflammation, generally four seasons can be seen, but in winter and early spring the most. The disease is usually rapid-onset, in order to chills, fever, chest pain, cough and rusty sputum is characterized by cough, chest X ray showed acute inflammatory lung segment or lobe consolidation. In recent years, due to extensive use of antimicrobial agents in clinical patients with mild or atypical symptoms, more and more See. [Keywords:] Streptococcus pneumoniae serotype distribution of antibiotics in respiratory tract infections First, the pathophysiology 1. Respiratory insufficiency mainly as hypoxemia, severe cases can have carbon dioxide retention. Pneumonia due to inflammation, on the one hand, the alveolar wall thickening, diffusion resistance increases, On the other hand, the bronchial mucosal hyperemia, edema and secretion retention, resulting in a relatively narrow lumen previously more narrow. Both resulting in severe dysfunction of ventilation and ventilation, hypoxia and hypercapnia. In disease early, the patient can increase the respiratory frequency and depth of breathing to increase the minute ventilation. As big than oxygen diffusing capacity of carbon dioxide, so patients are often only mild hypoxia early and there is no significant carbon dioxide retention. If the lesions progress, they will seriously hamper the effective gas exchange, so that arterial oxygen pressure (PaO2) and oxygen saturation (SaO2) decreased the occurrence of hypoxemia. if SaO2 fell to 85%, reduction of hemoglobin of 50g or more, you can see cyanosis If a serious lowering of pulmonary ventilation to carbon dioxide emission, it will simultaneously reduce PaO2 and arterial carbon dioxide partial pressure (PaCO2) increased [PaO2