PD-1 and its ligand in the role of chronic hepatitis B immunization.docVIP

 PAGE \* MERGEFORMAT 15 PD-1 and its ligand in the role of chronic hepatitis B immunization [Keywords:] Hepatitis B Immunization HBV-specific T lymphocytes and HBV to escape immune dysfunction caused by HBV is the cause of chronic persistent infection, T lymphocyte functional status determines the virus is cleared, or persistent infection. Abnormal expression of T lymphocytes in certain immune molecules in patients with chronic hepatitis B (CHB) of the occurrence and development processes. PD-1 as the CD28 family of recently discovered new member of its unique biological functions of co