Pegylated interferon in patients with hepatitis C caused by old women with symptoms of depression.doc

 PAGE \* MERGEFORMAT 9 Pegylated interferon in patients with hepatitis C caused by old women with symptoms of depression Of: Zhang Wenbin Wang Xinyi Liu Jinxia [Abstract] in elderly women with chronic hepatitis C patients treated with interferon before and after the occurrence of depression and anxiety and other adverse reactions. Methods 54 patients with different age and sex of chronic hepatitis C patients were divided into groups aged women (n = 13, older male group (n = 15, young group (n = 26. in the treatment before and after treatment, 12 w, respectively, of patients in each group self-test using Zung Depression Scale (ZDS) and the Zung anxiety self-rated scale (ZAS) for psychological evaluation, statistical analysis of the data. Results of interferon treatment, the patients in each group varying degrees of depression and anxiety increased, ZDS 3 groups followed by quantitative results (51.94 + -4.76, (42.85 + -5.96 and (44.61 + -4.32, ZAS quantify the result is (53.60 + -5.90, (41.78 + -6.57 and (38.29 + -6.63, integral value of older women significantly increased in patients with elderly male group, compared young patients There was a significant difference (all P lt;0.001. ZDS elderly women before and after treatment to quantify results (42.8 + -3.83, and (51.9 + -4.76, ZAS is to quantify the results (44.8 + -2.90, and (53.6 + -5.90, Zung quantitative integration also significantly higher (P lt;0.001. In addition, patients with depression and anxiety in patients with primary disease and disease-related trend exists, but not for small number of cases for statistical analysis. Conclusions Elderly patients with interferon treatment of women more prone to depression and anxiety symptoms, should be paid attention, timely adjustment of treatment. [Keywords:] pegylated interferon, older women, chronic hepatitis C, depression, anxiety Pegylated interferon (PEG IFN @ 2a treatment of chronic viral hepatitis (chronic hepatitis C) is better, but mainl