Perfusion CT of solitary pulmonary nodules and application of the blood flow characteristics.doc

 PAGE \* MERGEFORMAT 16 Perfusion CT of solitary pulmonary nodules and application of the blood flow characteristics [Abstract] Objective slice spiral CT perfusion imaging of solitary pulmonary nodules and to evaluate the blood perfusion in the differential diagnosis of benign and malignant nodules. Methods 44 patients with solitary pulmonary nodules underwent perfusion imaging , were obtained from the nodular blood flow (BF, blood volume (BV, mean transit time (MTT, permeability surface (PS value and fitting time - density curves (TDC, and may in time - based on the density curve, solitary pulmonary nodule enhancement measured before and after the CT value, peak enhancement, net enhancement value, peak time and other morphological indicators. the result of malignant lung nodules of BF, BV, PS peak enhancement value and enhance the net value-added, time to peak were higher than in benign pulmonary nodules, there were significant differences (P values #8203;#8203;were lt;0.05. benign and malignant nodules TDC different shapes. 25Hu net value added can be used as the threshold of malignant nodules. Conclusion CT perfusion imaging can reflect the isolated pulmonary hemodynamic characteristics of nodules, can be used for noninvasive diagnosis and evaluation of solitary pulmonary nodules. [Keywords:] solitary pulmonary nodules ray computed tomography perfusion [Abstract] Objective To investigate the blood flow features of solitary pulmonary nodule (SPN) using CT perfusion imaging and to evaluate the clinical value in differential diagnosis between benign and malignant SPN. Methods A total of 44 patients with solitary pulmonary nodules underwent perfusion scan with 16-slice spiral CT (LightSpeed; GE Medical Systems) scanner.The parameters of CT perfusion including blood volume (BV), blood flow (BF), mean transit time (MTT), permeability surface (PS) and time-density curve ( TDC) were analyzed.The peak height in density, net enhancement, enhancement value and