PETCT imaging agents in the diagnosis of age-related diseases.docVIP

 PAGE \* MERGEFORMAT 12 PETCT imaging agents in the diagnosis of age-related diseases OF: He Qi Wang Cheng Li Yinghua Lin Guan Feng Yu Dan [Keywords:] PET CT imaging agent; age-related diseases Positron emission tomography imaging (PET CT imaging), can be reflected in the molecular level of cell metabolism, cell receptors, nucleic acid synthesis and cell genetically modified so as to achieve the purpose of early diagnosis of disease. PET CT for noninvasive, dynamic, quantitative observed in the human body’s physiological and pathological process, has become an important method of tumor imaging and clinical staging, treatment options, efficacy evaluation, radiotherapy has an important value orientation, etc. (1). PET CT imaging agent (that is E-radioactive drugs) determines the development and application of the development of PET CT imaging. In this paper, PET CT imaging agent in the diagnosis of senile diseases, clinical application and development prospects are summarized. 1 PET CT imaging principle PET is the use of cyclotron to accelerate the charged particle bombardment of target nuclei, nuclear reactions that are e-radioactive elements, such 11C, 13N, 15O, 18F, etc., by chemical synthesis to obtain the corresponding radioactive tracer. Tracers into the body, in accordance with its properties in certain parts of the uptake, but the will to carry the radionuclide decay. decay process emitting positrons, which are electronic in the organization that runs 1 ~ 2 mm in the surrounding tissue with the electron interaction, annihilation radiation occurs, into the opposite direction of the two photons, PET detected this photon, and then re-imaging by computer, to obtain the distribution of tracer in the body (2.) 2 PET CT features of imaging agents PET CT imaging agent is labeled with a positron nuclide, preparation of radioactive imaging agent. Compared with ordinary drugs, PET CT imaging agent has the following characteristics: Positron rad