Placing emphasis on research designed to improve the quality of clinical research details.docVIP

 PAGE \* MERGEFORMAT 10 Placing emphasis on research designed to improve the quality of clinical research details With a good clinical research projects, if there is no scientific research design, even with the state’s key funding issues, it is hard to achieve the desired purpose, worse, may result in human, material and financial resources, in particular, a waste of precious time . According to a sample survey, in 1985 and 1995, two years, five kinds of Chinese Medical Association published in the journal 112 on the theory of the diagnostic test results showed that 90.0% more than reasonable research design papers. 16.0% of them the lack of ‘gold standard’ (goldstandard) assessment; 35.7% positive rate of literature reports only, without sensitivity, specificity, diagnostic and other basic indicators, but also not covered by the likelihood ratio and receiver operating characteristic curve (ROC) analysis and evaluation and so on. In the clinical study, the sample surveys from 1985 to 1996, 35 kinds of Chinese Medical Association published in the journal series of randomized controlled trials (RCT) study on a total of 164, which set out the method of randomization were only 15.2%; account of the random grouping method, but errors are 5.5%; as much as 79.3% on the study itself is a reference to randomized controlled trials, but the text simply no way on the randomization methods and narrative. As reported by stratified random controlled trials, then the contradictions more. In addition, the recent national clinical research projects focus on the incomplete evaluation and analysis, at present, research design flaws rate of about 30%. The existence of these problems very seriously impeded the improvement of China’s clinical research level, the clinical progress also has an important negative impact. Chinese Medical Association Society of Clinical Epidemiology, Clinical Epidemiology Collaboration in China and the China Committee of Medical Journal Editor