Plasma homocysteine levels and the relationship between microvascular complications of hypertension.doc

 PAGE \* MERGEFORMAT 10 Plasma homocysteine levels and the relationship between microvascular complications of hypertension Of: Rao Yiwu Zhou Xiaoli Li Ya-Peng Zhou Liqin new [Abstract] Objective To investigate the fasting plasma total homocysteine (tHcy levels and microvascular complications of hypertension and its related factors. Methods 112 cases of essential hypertension, in which no complication group (NHTC50 cases retinopathy (HTR30 cases, hypertension nephropathy group (HTN32 patients in the control group (C group, 40 cases. determined by enzyme immunoassay in plasma tHcy concentrations in blood pressure with ambulatory blood pressure health CAREBOY 180 EA recorder measurement. automatic biochemical Determination of serum creatinine (Scr, total cholesterol (TC), triglyceride (TG). radioimmunoassay determination of urinary albumin, and calculated the excretion rate per minute. Results HTR group and fasting plasma tHcy HTN group was significantly higher than the NHTC group and C group (P lt;0.01, high Hcy hyperlipidemia hypertensive nephropathy in hypertensive patients (HTN, hypertensive retinopathy (HTR were significantly higher than those without hyperlipidemia in hypertensive patients with tHcy (P lt;0.01 , pulse pressure (24 hPP, Scr tHcy were the decisive factor in patients with hypertension (P lt;0.01, Logistic regression analysis showed that fasting tHcy, body mass index (BMI, TC, 24 hPP and the occurrence of HTN, fasting tHcy, TC, Scr, 24 hPP HTR are independent risk factors. Conclusion fasting tHcy hyperlipidemia are risk factors for microvascular disease of hypertension, Scr, and the degree of lipid metabolism the concentration of tHcy. [Keywords:] cysteine, hypertension, hypertensive nephropathy, hypertension, retinopathy Plasma homocysteine (Hcy levels increased has been considered as the heart, brain, kidney and peripheral vascular disease, independent risk factors (1). In recent years, studies have shown that hypertension, the in