Po Gypenosides dry capsule combined with tablets in the treatment of hyperlipidemia in rats with fatty liver in rats.doc
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Po Gypenosides dry capsule combined with tablets in the treatment of hyperlipidemia in rats with fatty liver in rats
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Po Gypenosides dry capsule combined with tablets in the treatment of hyperlipidemia in rats with fatty liver in rats
Of: Lixu Hong, CHENG Wei-Dong, off Chengde, Dong Li
[Abstract] Objective Jiaogulan Joint Po dry capsule hyperlipidemic fatty liver in rats and its mechanism. Methods 42 rats were randomly divided into normal control group, model group, group Gynostemma, Jiaogulan Po dry group and the joint capsule Po dry capsule. In addition to the normal control group, other groups were fed high fat diet for 12 weeks, making fatty liver model, treatment group after the model was successfully given to the appropriate drug treatment for 4 weeks. serum total cholesterol ( TC, triglyceride (TG, aspartate aminotransferase (AST, alanine aminotransferase (ALT, liver index, superoxide dismutase (SOD) activity and malondialdehyde (MDA and liver tissue pathology. Results model group, the Gynostemma dry joint capsule can reduce Po TC, TG, AST, ALT, MDA and liver index, increased SOD activity. Conclusion Jiaogulan Joint Po dry capsule on to make fatty liver a good therapeutic effect.
[Keywords:] Gypenosides film, Po dry capsule, hyperlipidemia and fatty liver, SD rats
With China’s rapid economic development, living standards improve, people’s diet has changed, the long-term overeating fat, high cholesterol, low-fiber diets result in increased prevalence of fatty liver. Yangshu Xian et al discovered: fatty liver and the close relationship between hyperlipidemia and elevated triglycerides as the main features in [1]. At present there is a good medicine for the treatment of fatty liver function, Po dry capsules good results from clinical blood soup and self Tongmai to, so this experiment dry capsule Gynostemma Hubbell make fatty liver in rats and its mechanism study to provide a basis for clinical treatment.
1 Materials and equipment
1.1 Animals
SD rats of clean grade healthy selection of 42, male and female, body weight (180 + -25)
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