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Pituitary stalk interruption syndrome Clinical features of
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Pituitary stalk interruption syndrome Clinical features of
[Abstract] Objective To analyze, summarize pituitary stalk interruption syndrome (PSIS) of the clinical characteristics and endocrine function in income changes, improve the understanding and diagnosis of the disease. Methods PSIS 7 patients in our hospital clinical manifestations, endocrine experiments Room and imaging features. Results 7 patients 5 males and 2 females, mean age 5 to 29 years, 2 patients had history of difficult birth, the onset height 118 ~ 152 cm, 6 cases showed growth retardation, 1 patient showed dry mouth, polydipsia, polyuria and low specific gravity of urine. laboratory results suggest that: 5 patients had growth hormone deficiency, low gonadotropin hypogonadism and pituitary - adrenal insufficiency, 3 cases combined with secondary hypothyroidism; 1 patient only showed central diabetes insipidus; 1 patient before and after the current leaf pituitary endocrine function were normal. Magnetic resonance examination showed that all patients with smaller volume of the anterior pituitary and pituitary stalk shows unclear , No. pituitary normal Ye Gaoxin disappeared in 6 patients seen ectopic posterior pituitary, 1 cases with ChiariI deformity and C 1 ~ 4 hollow cone level of the spinal cord. Conclusion PSIS low incidence, diagnosis mainly depends on the magnetic resonance examination, there may be anterior and posterior lobe dysfunction, the condition early, when the pituitary stalk was not completely blocked, also without pituitary dysfunction.
[Keywords:] pituitary stalk interruption syndrome; growth retardation; clinical features
[Abstract] Objective To improve the accuracy of the clinical diagnosis of pituitary stalk interruption syndrome (PSIS) and improve its knowledge and diagnosis.Methods Seven cases (five males and two females) were retrospectively reviewed in terms of clinical manifestations, laboratory findings and imaging features.R
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