Polyclonal cell lines of research value - J6 1 human leukemia cell lines for 30 years A Review.docVIP

 PAGE \* MERGEFORMAT 33 Polyclonal cell lines of research value - J6 1 human leukemia cell lines for 30 years A Review Authors: WU Ke-fu, Zheng light, Ma Xiaotong Abstract J6  1 cell line is China’s establishment of the first strains of human leukemia cell lines are EBV and HHV  6 dual infections polyclonal cell lines. J6  1 cell lines Lines and 30 years, from the J6  1 cell clone a number of cytokines, receptors and other genes, providing a lot about the nature and function of leukemic cells of information, which spawned a number of research projects, all of which Polyclonal cell lines showed unique research value. In this paper, the past 30 years J6  1 human leukemia cell lines to make a comment on the study, including the J6  1 cell lines and multi-clonal heterogeneity, J6  1 cell population’s survival mechanism and J6  1 cell line abnormal cell communication and its significance, as well as the J6  1 cell line revelation. Keywords: leukemia cell line Research Value of Multi  clone Cell Line: A Comment for the 30th Anniversary of J6  1 Human Leukemic Cell Line - Editorial Abstract J6  1 cell line is the first leukemic cell line established in China. It is a multi  clone cell line infected with both EBV and HHV  6. Many cytokines, receptors and other genes were cloned from J6  1 cell line since its establishment 30 years ago. Valuable information on leukemic characteristics and functions were obtained from the studies on this cell line, which could be categorized into several research subjects. These achievements implied the unique research value of multi  clone cell lines. This comment focuses attention on research advance of the J6  1 leukemic cell line in 30 years, including heterogeneity and multi  cloning of J6  1 cells, survival mechanism of J6  1 cell populations, abnormal intercellalar communication of J6  1 cells with its significance and inspiration from J6  1 cell line. Keywords: leuk