Postmenopausal bone mineral density in patients with type 2 diabetes and related factors.doc

 PAGE \* MERGEFORMAT 7 Postmenopausal bone mineral density in patients with type 2 diabetes and related factors Study: Luan Xiaojun Chen Jinsong Hu Lidong [Keywords:] Type 2 diabetes; bone mineral density; Osteoporosis; postmenopausal Diabetes mellitus (DM) in patients with osteoporosis (OP) morbidity and risk of fracture increased significantly, OP has become a major cause of disability in patients with DM. Present women with type 2 diabetes mellitus (T2DM) patients with bone mineral density (BMD) levels and the risk of OP are not consistent (1 to 2). we measured BMD in postmenopausal patients with the level of T2DM, and analyze the related factors affect the BMD, in postmenopausal T2DM patients for clinical prevention and treatment of OP reference. 1 Subjects and methods 1.1 The object of study for the hospital medical control group of healthy postmenopausal women, aged 55 to 73 years (mean 63.5 + -6.1) years of age, menopause duration (12.3 + -5.3) years, body mass index (BMI) 24.4 + -3.3, A total of 58 cases. Endocrinology, Diabetes group of hospital outpatient and inpatient menopause with type 2 DM patients (diagnosed according to WHO criteria), aged 52 to 76 years (mean 65.7 + -7.5) years, DM duration (6.7 + -2.3 ) years, menopause duration (13.1 + -4.9) years, body mass index (BMI) 25.3 + -4.6, a total of 126 cases. All of the above subjects had no other diseases affecting bone metabolism and related drug treatment history, serum creatinine levels were normal. 1.2 Methods used by the U.S. company DELPHI fan beam Hologic DEXA, measurement of lumbar spine (L2 4) and the left proximal femur: femoral neck (Neck), greater trochanter (Troch), Waugh’s triangle (Ward’s) of the BMD. Diabetes Group fasting blood glucose (FBG), postprandial 2 h blood glucose (2hPBG), glycosylated hemoglobin (HbA1c), fasting serum C peptide (FCp), postprandial 2 h serum C peptide (2hPCp), blood lipids: triglycerides (TG) , total cholesterol (TC), high density lipop