Pregnant women the level of lipid metabolism associated with macrosomia occurred in study.docVIP

 PAGE \* MERGEFORMAT 14 Pregnant women the level of lipid metabolism associated with macrosomia occurred in study 【Abstract】 Objective: To investigate the level of lipid metabolism in pregnant women occurred in the relationship between macrosomia. Methods: 2244 patients with non-pregnant women with diabetes, pregnant women in late pregnancy serum fasting blood glucose (FBG), total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL  C), low density lipoprotein cholesterol (LDL  C), apolipoprotein A Ⅰ (Apo A Ⅰ) and apolipoprotein B (Apo B) levels, detailed record of maternal age, pregnancy times, pre-pregnancy weight, height, birth gestational age, laboratory data, and neonatal sex, weight, according to neonatal birth weight infants were divided into large groups and normal birth weight group were compared. Results: (1) macrosomia group of pregnant women TG, Apo B levels were significantly higher than normal birth weight group (P lt;0.001), while HDL  C, Apo A Ⅰ level was significantly lower than normal birth weight group (P lt;0.05), 2 group of pregnant women between TC, LDL  C levels was no significant difference (Pgt; 0.05); (2) high cholesterol group of pregnant women, the incidence of macrosomia was higher than the normal lipid group (P = 0.011); (3) birth weight of newborns and maternal serum TG level was significantly positively correlated (r = 0.315, P lt;0.001). Conclusion: The attention to monitoring of pregnant women during pregnancy, blood lipid changes in the proportion of a balanced diet, controlling blood lipids, for the prevention of the occurrence of macrosomia has clinical significance. Keywords: blood lipids; pregnant women; neonatal birth weight; macrosomia Macrosomia are the birth weight ≥ 4 000 g of the newborn. Macrosomia not only increase production when the post-natal maternal and neonatal risks, but also after birth and newborn metabolic diseases closely related to the prevention of