Preparation Carboxymethylpachymaran and Antineoplastic Studies.doc

 PAGE \* MERGEFORMAT 11 Preparation Carboxymethylpachymaran and Antineoplastic Studies [Abstract] Objective To investigate the Carboxymethylpachymaran Preparation and antitumor activity. Methods exist in the next method is simple halogenated acid Carboxymethylpachymaran prepared and were studied in vivo, in vitro antitumor activity. Results with the control group, in the inhibition of Carboxymethylpachymaran Kunming mice H22 hepatoma cells and mouse tumor cell activity U 14 has a significant effect. conclusions obtained by simple method to prepare can significantly improve the immunity of tumor-bearing mice carboxylase methyl CMP, the appropriate dose Carboxymethylpachymaran good antitumor activity. [Keywords:] Preparation Carboxymethylpachymaran anti-tumor activity [Abstract] Objective To study the preparation and the anti tumor effects of carboxymethyl pachyman.Methods Carboxymethyl pachmaran was prepared conveniently in one step process with the presence of halogenated acid. The anti tumor effects of carboxymethyl pachmaran in vivo and in vitro were studied respectively. Results There were significant effect of the carboxymethyl pachyman for inhibition on murine 22 hepatocarcinoma cell and murine U 14 Cancer Cells comparing with control group.Conclusion Carboxymethyl pachyman can be prepared conveniently. Proper dose of carboxymethyl pachyman has a good anti tumor effect. [Keywords:] carboxymethyl pachyman, preparation, anti tumor effect Poria is commonly used in Chinese medicine, also belong to a kind of strong medicine, first seen in the Tang Dynasty lt;”New Revised Materia Medicagt;gt;:” ... this transfer business and management stomach, top grade Xianyao also. Good to break Google is not hungry, no rust for the drug Boring ... “(Volume XII) [1], for the families Polyporaceae fungi Poria Poria cocos (Schw.) Wolf of the dried sclerotia, patients with spleen Lee, Ning Anshen and other effects. cocos sclerotium of polysaccharides in the Poria