Preparation of a new method of schisandrin_0.doc

 PAGE \* MERGEFORMAT 11 Preparation of a new method of schisandrin OF: He Tao, Mushu Zhen, Hao Xiaojiang, Zhou Ying, Zhang Jianxin and the Paths [Abstract] Objective To establish a simple and effective preparation of the new schisandrin. Methods north of the dried ripe fruit of Schisandra as raw material, followed by ethanol extraction, liquid - liquid extraction, silica gel column chromatography, macroporous resin column chromatography, repeated recrystallization steps can be prepared Schizandrin high purity. The results by this method can be rapid and effective preparation of high purity Schizandrin. conclusion provides a new preparation schisandrin methods. [Keywords:] Schisandra; schisandrin; macroporous resin; recrystallization; method Schisandra Schisandra is a Chinese Medicine Branch, plant Schisandra Schisandra Schisandra chinensis and Schisandra sphenanthera Schisandra sphenanthera Rehd. Etwils dry ripe fruit, trade names are “Schisandra” and “Kadsura.” Schisandra Pickle, sweet, warm, the lung, heart, kidney. lt;lt;Shen Nong’s Herbal Sutra “gt; will Schisandra as a top grade, which has a convergence Guse, Qi Sheng Jin, kidney and heart effect Ning, attending a long time cough virtual asthma, nocturnal emission, Hua Jing, enuresis, frequent urination, more than Jiuxie, sweating, thirst Tianjin injury, short Qimai true, heat diabetes, heart palpitation, insomnia and other diseases, rich in Liaoning, Jilin, Heilongjiang and Hebei. pharmacological studies have shown that , Schisandra in many aspects a good effect, a wide range of clinical applications, especially for carbon tetrachloride, thio acetic acid amine cause liver damage caused by SGPT (serum alanine aminotransferase) increased with decreasing effect, but also hepatitis patients can reduce the high SGPT, liver damage may also reduce the toxic substance metabolism, with a slightly increased glycogen and reduce degeneration of liver cells, reducing poisoning causative agent of liver cell